Property
ActiveResidential
1/28
$1,150,000

422 21st Street

Denver, CO 80205
4
Beds
2
Baths
2,565
SqFt
0.14
Acres
RECOLORADO
#6487194
Updated: Jun 24, 2026, 1:30pm

Property Description

Located in the heart of Five Points, this unique for-sale offering presents a compelling investment, owner-user, or redevelopment opportunity on a highly visible 6,270 SF corner lot just steps from Downtown Denver, Uptown, and the vibrant Five Points district. The property consists of a well-maintained single-family home and an adjacent office duplex, providing multiple income streams and flexible future potential. The approximately 2,565 SF single-family residence features four bedrooms and two bathrooms and is most recently operated as a successful Airbnb, offering immediate short-term rental income or the option for an owner-user residence. The office duplex is comprised of two office units of approximately 2,000 SF each, both tenant-occupied on month-to-month leases, allowing for steady income with near-term flexibility for repositioning or redevelopment. With its premier corner location, walkability to Denver’s central business district, and proximity to restaurants, nightlife, transit, and cultural amenities, this property offers
exceptional upside in one of Denver’s most dynamic and rapidly evolving neighborhoods.

Property Details

Interior
Above Grade Finished Area
2565
Building Area Total
2565
Cooling
None
Heating
Hot Water
Living Area
2565
Room Count
8
Construction
Also Marketed As
Residential IncomeCommercial SaleResidential
Building Area Source
Public Records
Construction Materials
Brick
Levels
Two
Roof
Composition
Structure Type
House
Year Built
1886
Site & Exterior
Lot Features
Level
Lot Size Acres
0.14
Lot Size Area
6270
Lot Size Square Feet
6270
Lot Size Units
Square Feet
Sewer
Public Sewer
Water Included
Yes
Zoning
C-MX-5
Financials
Contract Earnest Check To
Land Title Guarantee Company
Contract Min Earnest
20000.00
Exclusions
Personal Property.
Ownership
Individual
Parcel Number
2341-27-015
Special Listing Conditions
None
Tax Annual Amount
15636
Tax Legal Description
CLEMENTS ADD B191 L1 & 2
Tax Year
2024
Title Company
Land Title Guarantee Company

Neighborhood & Lifestyle

Community & Association
Senior Community
No
Subdivision Name
Five Points
Schools
Ratings
Elementary
Whittier E-8
Middle
Cole Arts And Science Academy
High
East
Elem. District
Denver 1
Middle District
Denver 1
High District
Denver 1
Listing provided courtesy of RECOLORADO via IDX. Updated: Jun 24, 2026, 1:30pm.
Karen Zeile

Listing Agent

Kentwood Commercial, Llc

Call Agent